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Anne Murphy

Associate Professor    Faculty    ,

University of Cincinnati BS 1985 Psychology
University of Colorado Masters 1987 Behavioral Genetics
University of Cincinnati Ph.D. 1992 Behavioral Neurosci.
University of Maryland Postdoctoral 1995 Neurobiology


Behavioral Neuroscience
Developmental Neuroscience
Sex Differences


Dr. Anne Z. Murphy joined the faculty of Georgia State University in 2003, and is currently an Associate Professor in the Neuroscience Institute. She received her Ph.D. from the University of Cincinnati in 1992 under the guidance of Dr. Michael Behbehani (Dept. Physiology). She then completed postdoctoral fellowships in Behavioral Neuroanatomy with Dr. Michael Shipley at the Univ. Maryland, Baltimore and in Behavioral Neuroendocrinology with Dr. Gert Holstege at the Rijksuniversitiet in the Netherlands. Before joining the faculty at Georgia State University, Dr. Murphy was a Research Associate Professor at the University of Maryland School of Medicine. Dr. Murphy’s research focuses on the impact of sex and age on pain and opiate responsiveness as well as the impact of early life experience on adult pain and stress responsiveness. She uses a wide variety of techniques from molecular to behavioral to describe how pain alters brain activity and synaptic plasticity. The goal of this work is to elucidate the mechanisms whereby age, sex and early life experience alter opioidergic circuits within the CNS. She has received numerous research grants from the National Institutes of Health to support her work. Dr. Murphy is also on the editorial board of several journals, reviews grants regularly for NIH and NSF, and is the Associate Director of the Neuroscience Institute. When not doing science, Dr. Murphy loves to hang out on the beach with her husband and kids.


Representative Publications
Eidson, L. N. and Murphy, A.Z. Persistent peripheral inflammation attenuates morphine-induced periaqueductal gray glial cell activation and analgesic tolerance in the male rat. J. of Pain 14 (2013) 393-404.

Victoria, N.C., Inoue, K., Young, L.Y. and Murphy, A.Z. A Single Neonatal Injury Induces Life-Long Deficits in Stress Responsiveness and Increases Brain Enkephalin Expression. Develop. Neurosci. 35 (2013) 326-337.

Eidson, L. N. and Murphy, A.Z. Blockade of Toll-like Receptor 4 Attenuates Morphine Tolerance and Facilitates the Pain Relieving Properties of Morphine. J. Neuroscience 40 (2013) 15952-15963.

Victoria, N.C., Inoue, K., Young, L.Y. and Murphy, A.Z. Long-term dysregulation of brain corticotrophin and glucocorticoid receptors and stress reactivity by single early-life pain experience in male and female rats. Psychoneuroendocrinology 38 (2013) 3015-3028.

Victoria, N.C., Eichenbaum, H., Karom, M. and Murphy, A.Z. Neonatal Injury Rapidly Alters Markers of
Pain and Stress in Rat Pups. Developmental Neurobiology, 74 (2014) 42-51.
Loyd, D.R. and Murphy, A.Z. The Neuroanatomy of sexual dimorphism in pain and opioid analgesia.
Experimental Neurol. (2014) pii: S0014-488600099-5. doi: [Epub ahead of print]

Find Anne Murphy’s publications on PubMed