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Anne Murphy

Professor    , ,

University of Cincinnati BS 1985 Psychology
University of Colorado Masters 1987 Behavioral Genetics
University of Cincinnati Ph.D. 1992 Behavioral Neurosci.
University of Maryland Postdoctoral 1995 Neurobiology


Behavioral Neuroscience
Developmental Neuroscience
Sex Differences


Dr. Anne Z. Murphy joined the faculty of Georgia State University in 2003, and is currently an Associate Professor in the Neuroscience Institute. She received her Ph.D. from the University of Cincinnati in 1992 under the guidance of Dr. Michael Behbehani (Dept. Physiology). She then completed postdoctoral fellowships in Behavioral Neuroanatomy with Dr. Michael Shipley at the Univ. Maryland, Baltimore and in Behavioral Neuroendocrinology with Dr. Gert Holstege at the Rijksuniversitiet in the Netherlands. Before joining the faculty at Georgia State University, Dr. Murphy was a Research Associate Professor at the University of Maryland School of Medicine. Dr. Murphy’s research focuses on the impact of sex and age on pain and opiate responsiveness as well as the impact of early life experience on adult pain and stress responsiveness. She uses a wide variety of techniques from molecular to behavioral to describe how pain alters brain activity and synaptic plasticity. The goal of this work is to elucidate the mechanisms whereby age, sex and early life experience alter opioidergic circuits within the CNS. She has received numerous research grants from the National Institutes of Health to support her work. Dr. Murphy is also on the editorial board of several journals, reviews grants regularly for NIH and NSF, and is the Associate Director of the Neuroscience Institute. When not doing science, Dr. Murphy loves to hang out on the beach with her husband and kids.


Find Anne Murphy’s publications on PubMed

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Representative Publications

Doyle, H.H., L.N. Eidson, D. Sinkiewicz and Murphy, A.Z.  Sex Differences in Microglia Activity within the Periaqueductal Gray of the Rat: A Potential Mechanism Driving the Dimorphic Effects of Morphine. J Neurosci 37 (2017) 3202-3214.

Eidson, L.N., Inoue, K., Young, L.J., Tansey, M.G. and Murphy, A.Z. Periaqueductal gray toll-like receptor 4 modulates morphine tolerance via soluble tumor necrosis factor signaling. Neuropsychopharmacology 42 (2017) 661-670.

Victoria, N.C. and Murphy, A.Z. Exposure to Early Life Pain: Long Term Consequences and Contributing Mechanisms. Current Opinion in Behavioral Sciences.  7 (2016) 61-68.

Victoria, N.C. and Murphy, A.Z. The long-term impact of early life pain on adult anxiety and stress: Historical perspectives, the clinic and empirical evidence. Experimental Neurol 275 Pt 2 (2016) 261-73.

Eidson, L. N. and Murphy, A.Z. Blockade of Toll-like Receptor 4 Attenuates Morphine Tolerance and Facilitates the Pain Relieving Properties of Morphine. J. Neuroscience 40 (2013) 15952-15963.
Find Anne Murphy’s publications on PubMed